THC Genetic Test

Your THC genetic profile with personalized reports and actionable insights, delivered directly to your smartphone.

  • Metabolism: Understand your sensitivity to THC
  • Mental Health: Explore your short and long-term risk factors for mental health risk associated with THC use
  • Memory: Discover how THC can affect your memory
  • Product recommendations based on your unique genetic results
  • Future updates: Latest research and studies, recommendations and exclusive offers
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Your sensitivity to THC

The way your body metabolizes THC, the intoxicating compound in cannabis, is influenced by the CYP2C9 gene. This gene encodes a liver enzyme that helps metabolize THC in your bloodstream. 15–20% of people carry the CYP2C9*3 genetic variant which causes them to metabolize THC up to 2x to 3x slower than normal.

These ‘slow metabolizers’ should be more cautious when consuming THC, as they will likely experience an increased duration and intensity of intoxication, especially when taking THC in oral form.

Metabolism report includes
  • Insight into intensity and duration of effects (smoking, edibles and oils)
  • Genetics by population and ethnicity
  • How metabolism can influence drug testing and much more

Your risk for THC-related mental health issues

THC's intoxicating effect or ‘high’ is caused by the release of dopamine in the brain. However, too much dopamine can trigger an increased risk of psychotic symptoms including hallucinations and paranoia.

The AKT1 gene plays an important part in the dopamine signaling pathway in the brain. 25% of people carry the AKT1 C/C genotype that can cause an increased risk for short and long-term THC-induced psychosis and schizophrenia. While all users of THC have a baseline risk for psychosis, AKT1 C/C carriers should be particularly aware of their elevated risk profile.

Risk report includes
  • Short-term risk of psychotic effects
  • Long-term risk of psychosis and schizophrenia
  • Genetics by population and ethnicity
  • THC and brain chemistry and more

How THC affects your memory

Dopamine plays an important role in learning and memory formation. The COMT gene influences how quickly dopamine is cleared from the brain. 30% of people carry the COMT Val/Val genotype, which causes them to clear dopamine more quickly. As a result, these individuals generally have lower dopamine levels.

Studies have shown that COMT Val/Val carriers suffer from more neurocognitive impairments when using THC, including up to a 40% reduction in short-term memory.

Memory report includes
  • Neurocognitive impairment risk, including memory loss
  • Genetics by population and ethnicity
  • Your stress response — are you a ‘Warrior’ or ‘Worrier’?

Explore your THC genetic profile and more

In addition to your reports, we're constantly updating our platform to bring you future insights and benefits including:

  • Tools and recommendations to better understand your cannabis profile
  • The latest science and research news
  • Exclusive offers from our partners

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